Capillary Electrophoresis (CE) has demonstrated its wide potential to solve many analytical problems. Recent
developments in CE with contributions for sample preparation, improvements in detection and aspects associated with application
and productivity requirements in routine laboratories are reviewed and discussed. Although these capabilities of
CE, the transference of CE methods to routine analytical work is very limited. The main contributions and advantages of
CE with respect other instrumental separation techniques are summarized in this article, and also the scarce use in routine
laboratories is critically discussed. After this balance, the arguments to identify the ‘analytical niche’ of CE in applied
analytical laboratories are reported.