Title:Cinchona Alkaloid-Catalyzed Stereoselective Carbon-Carbon Bond Forming Reactions
VOLUME: 2 ISSUE: 1
Author(s):Srinivasarao A. Babu, Ramasamy V. Anand and Sripada S.V. Ramasastry
Affiliation:Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, SAS Nagar, Mohali, Manauli P.O., Punjab, India, 140306.
Keywords:Asymmetric synthesis, Cinchona alkaloids, C-C bond formation, diastereoselectivity, enantioselectivity, organocatalysis.
Abstract:This review provides insights into the patents available on one of the subfields of organocatalytic reactions,
specifically, the Cinchona alkaloids-based organocatalytic reactions, involving asymmetric C-C bond construction. Some
of the very important achievements in the asymmetric carbon-carbon bond formation by employing the Cinchona alkaloids-
based organocatalysts, one of the privileged classes of asymmetric catalysts, have been accentuated. The Cinchona
alkaloids-based enantio- and diastereoselective syntheses of a range of amino acid derivatives, bioactive molecules and
various synthetic intermediates with high efficiency are also highlighted.
