Translational Application of In Vivo Imaging and Analysis of Atherosclerotic Plaque Vulnerability Assessment

Author(s): Kiyoko Uno, Yu Kataoka, Rishi Puri, Stephen J. Nicholls

Journal Name: Recent Patents on Medical Imaging
Continued as Recent Patents and Topics on Imaging

Volume 3 , Issue 1 , 2013


Whereas atheroma progression/regression studies have focused on luminal narrowing or atheroma burden, the current notion that inflammation and immune response may contribute to the development of plaque rupture has garnered increased interest. As the disease process has become increasingly defined, this provides a range of potential targets to be employed by emerging imaging techniques. With ongoing developments in vascular imaging to visualize compositional and biological features in atherosclerotic plaque, there is considerable interest in the incremental information that can be ascertained. A selective overview of emerging modalities and patents to image the artery wall and the potential target is summarized.

Keywords: Anatomical imaging, arterial wall imaging, cardiovascular event, intravascular ultrasound, molecular targeted imaging, vulnerable plaque.

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Article Details

Year: 2013
Page: [14 - 26]
Pages: 13
DOI: 10.2174/1877613211303010004
Price: $65

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PDF: 13