A novel route for the synthesis of tetrahydroimidazo [1,2-a] pyrimidine-6-carboxylate derivatives in presence
of 1-ethyl-3-methyl imidazolium hydrogen sulphate ionic liquid at room temperature has been reported via Biginelli reaction.
The process offer several advantages such as short reaction time, excellent yield of products, simple work up procedure
etc. 1-ethyl-3-methyl imidazolium hydrogen sulphate ionic liquid is utilized as solvent system and catalyst to enhance
the rate of reactions.
Keywords: Aromatic aldehydes, Biginelli reaction, Catalyst, Ionic liquid, 5-amino-4, 5-dihydro-1H-pyrazole-4-carbonitrile
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