The Role of Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease Diagnosis. Where are we Now?

Author(s): Vasileios T. Papaliagkas

Journal Name: Recent Patents on CNS Drug Discovery (Discontinued)

Volume 8 , Issue 1 , 2013


Alzheimer’s disease (AD) is a rapidly growing disease that is estimated to affect about 36 million people worldwide, therefore there is an immediate need for its’ early diagnosis and treatment. A number of research studies are performed on possible accurate and reliable diagnostic biomarkers of AD. This review study provides an update on the cerebrospinal fluid (CSF) proteins that are being currently used in clinical practice and studied as biomarkers for early AD diagnosis and their future prospects, as well as relevant patents.

Keywords: Alzheimer’s disease (AD), Abeta42, cytochrome c, secretases, Tau.

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Article Details

Year: 2013
Page: [70 - 78]
Pages: 9
DOI: 10.2174/1574889811308010006

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