Title:Synthesis and Biological Applications of Triazole Derivatives – A Review
VOLUME: 10 ISSUE: 1
Author(s):S. Sathish Kumar and Helen P. Kavitha
Affiliation:Department of Chemistry, SRM University, Ramapuram campus, Chennnai-89, India.
Keywords:Anticancer, antihistaminic, antimycotic, analgesic, antiinflammatory, cytotoxic, synthesis, triazole compounds
Abstract:There has been considerable interest in the development of novel heterocyclic compounds with varied biological
activities. Triazoles are a special class of heterocyclic compounds with a broad spectrum of biological activities such
as antimicrobial, cytotoxic, antihistaminic, anticonvulsant, analgesic, anti-inflammatory, insecticidal, antimycotic, antimycobacterial,
anticancer, antiprotozoal, antimalarial and anti-ulcer activity. Therefore, many researchers have synthesized
these compounds as target structures and evaluated their biological activities. These observations help the researchers
for the development of new triazole compounds with enhanced biological activities. This review focuses on the various
synthetic strategies followed for the synthesis of triazoles, and their biological activities.
