Ischemic stroke represents one of the major causes of mortality and disability in the adult population in both
developed and developing nations. Considering these epidemiological issues, the improvement of preventive therapeutic
strategies has been recently targeted as a pivotal research field for scientific community. On the basis of the results from
several large clinical studies and metanalyses, some Task forces of researchers from recognized Scientific Societies have
recently produced some consensus Guidelines, recommending the use of statins as a key pharmacologic approach in
stroke prevention. In the present narrative review, we will update evidence on safety and efficacy of statins to prevent
ischemic cerebral stroke.
Keywords: Statins, atherosclerotic plaque, stroke.
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