Title:PET-MRI Based Molecular Imaging as a Response Marker in Cervical Cancer: A Systematic Review
VOLUME: 2 ISSUE: 1
Author(s):Supriya Chopra, Tapas Dora, Sunita Dhanda, Venkatesh Rangrajan and Shyam Kishore Shrivastava
Affiliation:Department of Radiation Oncology, Advanced Centre for Treatment Research, and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.
Keywords:Cervix, diffusion-weighted MRI, dynamic contrast-enhanced MRI.F-Miso, FLT, FDG, Molecular Imaging, "Cervical
Cancer, Therapeutic strategies, proliferation, angiogenesis
Abstract:Therapeutic strategies continue to evolve for treatment of women with cervical cancer. However there is dearth
of validated biomarkers of therapeutic response and overall survival. In recent years development of molecular imaging
techniques using Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) has allowed evaluation
of imaging biomarkers of proliferation, angiogenesis, perfusion and hypoxia as prognostic imaging biomarkers. The present
systematic review summarizes the current role of multifunctional PET and MRI as a response biomarker for cervical
cancer.
