Solvent-free and Water Mediated Synthesis of 2-Substituted Imidazolines Using Iron (III) Phosphate

Author(s): Farahnaz K. Behbahani, Toktam Sheibani Daloee, Parisa Ziaei.

Journal Name: Current Organic Chemistry

Volume 17 , Issue 3 , 2013

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Abstract:

Aldehydes were respectively converted to the corresponding 2-imidazolines in good yields by the reaction with ethylenediamine using iron (III) phosphate on water under reflux condition. Furthermore nitriles were converted to the corresponding 2-imidazolines under solvent-free condition at 100 °C. Utilizing of heterogeneous and recyclable catalyst, water as a solvent and solvent-free condition is the best medium from a green chemistry standpoint.

Keywords: Green chemistry, Iron (III) phosphate, Imidazoline, Solvent-free, Water mediated, Reusability of the Catalyst, Iron (III) phosphate, Antihypertensive, Antialzimer, Antitumor

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Article Details

VOLUME: 17
ISSUE: 3
Year: 2013
Page: [296 - 303]
Pages: 8
DOI: 10.2174/1385272811317030010
Price: $58

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