The Right Ventricle: Biologic Insights and Response to Disease: Updated

Author(s): Lori A. Walker, Peter M. Buttrick

Journal Name: Current Cardiology Reviews

Volume 9 , Issue 1 , 2013

Become EABM
Become Reviewer
Call for Editor


Despite ample evidence that right ventricular function is a critical determinant of the clinical response to a spectrum of cardiovascular diseases, there has been only a limited analysis of the unique and distinguishing physiologic properties of the RV under normal circumstances and in response to pathologic insults. This knowledge deficit is increasingly acknowledged. This review highlights some of these features and underscores the fact that rational therapy in RV failure needs to acknowledge its unique physiology and ought to be chamber specific. That is proven therapies for LV dysfunction do not necessarily apply to the RV. The updated version of this review now acknowledges recent advances in the understanding of metabolic, inflammatory and gender-specific influences on the right ventricle.

Keywords: Right ventricle, cardiomyocyte stucture-function, physiology, pathophysiology

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2013
Page: [73 - 81]
Pages: 9
DOI: 10.2174/1573403X11309010009

Article Metrics

PDF: 43