Recent Studies of Antioxidant Quinoline Derivatives

Author(s): M. Orhan Puskullu, Betul Tekiner, Sibel Suzen

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 13 , Issue 3 , 2013

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Quinoline derivatives constitute an important class of compounds for new drug development. As a large number of experimental and theoretical studies have shown that the quinoline ring system is an important structural unit widely existing in alkaloids, therapeutics and synthetic analogues with exciting biological activities. The present review provides recent antioxidant activities covering in vivo and in vitro studies of natural and synthetic analogues, as well as the proposed mechanisms of action and structure-activity relationships.

Keywords: Antioxidant activity, free radical, quinoline, oxidative stress

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Article Details

Year: 2013
Published on: 29 January, 2013
Page: [365 - 372]
Pages: 8
DOI: 10.2174/1389557511313030005
Price: $65

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