Title:Quinones Derived from Plant Secondary Metabolites as Anti-cancer Agents
VOLUME: 13 ISSUE: 3
Author(s):Jin-Jian Lu, Jiao-Lin Bao, Guo-Sheng Wu, Wen-Shan Xu, Ming-Qing Huang, Xiu-Ping Chen and Yi-Tao Wang
Affiliation:State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Av. Padre Toma’s Pereira S.J., Taipa, Macao, China;
Keywords:Quinone, Plant, Secondary metabolites, Tumor
Abstract:Quinones are plant-derived secondary metabolites that present some anti-proliferation and anti-metastasis effects in various
cancer types both in vitro and in vivo. This review focuses on the anti-cancer prospects of plant-derived quinones, namely, aloe-emodin,
juglone, β-lapachol, plumbagin, shikonin, and thymoquinone. We intend to summarize their anti-cancer effects and investigate the
mechanism of actions to promote the research and development of anti-cancer agents from quinones.
