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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents

Author(s): Jianping Yong, Canzhong Lu and Haji Akber Aisa

Volume 13, Issue 2, 2013

Page: [310 - 315] Pages: 6

DOI: 10.2174/1389557511313020012

Price: $65

Abstract

Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.

Keywords: Rupestonic acid derivatives, anti-influenza virus, structure-activity relationship

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