Title:Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents
VOLUME: 13 ISSUE: 2
Author(s):Jianping Yong, Canzhong Lu and Haji Akber Aisa
Affiliation:State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, P. R. China.
Keywords:Rupestonic acid derivatives, anti-influenza virus, structure-activity relationship
Abstract:Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with
multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of
rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review
describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.
