Abstract
A concise chemical synthesis of the common tetrasaccharide corresponding to the O-antigen of enteroinvasive Escherichia coli O143 and Shigella boydii type 8 has been achieved in excellent yield. Application of [2+2] block glycosylation and late stage oxidation of primary hydroxyl groups to the carboxylic groups are notable features in the synthetic strategy.
Keywords: Escherichia coli, Shigella boydii, O-antigen, tetrasaccharide, dysentery
Current Organic Synthesis
Title:Synthesis of a Common Tetrasaccharide Repeating Unit of the O-antigen of Enteroinvasive Escherichia coli O143 and Shigella boydii Type 81
Volume: 10 Issue: 1
Author(s): Abhishek Santra and Anup Kumar Misra
Affiliation:
Keywords: Escherichia coli, Shigella boydii, O-antigen, tetrasaccharide, dysentery
Abstract: A concise chemical synthesis of the common tetrasaccharide corresponding to the O-antigen of enteroinvasive Escherichia coli O143 and Shigella boydii type 8 has been achieved in excellent yield. Application of [2+2] block glycosylation and late stage oxidation of primary hydroxyl groups to the carboxylic groups are notable features in the synthetic strategy.
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Santra Abhishek and Kumar Misra Anup, Synthesis of a Common Tetrasaccharide Repeating Unit of the O-antigen of Enteroinvasive Escherichia coli O143 and Shigella boydii Type 81, Current Organic Synthesis 2013; 10 (1) . https://dx.doi.org/10.2174/1570179411310010010
DOI https://dx.doi.org/10.2174/1570179411310010010 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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