Non-dipping is a common pattern of arterial hypertension and it is associated with increased cardiovascular
risk. Use of ambulatory blood pressure monitoring, as suggested in recent guidelines, could further increase its prevalence
among subjects with hypertension. In this review we discuss assessment, relevance and associated factors. Non-dipping
could be addressed through chronotherapy, the use of specific classes of anti-hypertensives, such as renin-angiotensin
blockers, or modification of associated factors. However, more data are needed in order to comprehensively estimate factors
associated with non-dipping and how they could be modified.