Blood Pressure Variability and Mortality in end Stage Renal Disease

Author(s): Maria L. Sirico, Serena Torraca, Lucia Di Micco, Biagio Di Iorio

Journal Name: Current Hypertension Reviews

Volume 8 , Issue 4 , 2012

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Blood pressure (BP) measurement is a simple, and reproducible methool and is easily accepted by patients. It is well known that in a single subject BP may change during the day; this fact is considered physiological by many physicians and does not influence the final estimated value of BP. However, it’s reasonable to suppose that blood pressure variability (BPV) has clinical consequences and that exists a cardiovascular risk related to it. In fact, recent observations indicate that BP variations could be responsible for organ damage associated with hypertension more than the systolic and diastolic BP.

In this study, we aim to analyze and compare published data in literature concerning the presumable correlations between BP variability and outcomes, both in Chronic Kidney Disease (CKD) and End stage Renal Disease (ESRD). We conclude that BPV represents an important cardiovascular risk factor for both patients with CKD and for those in dialysis. No correlations were found between BPV and the progression of CKD. However, this is a retrospective study and more (RCTS) are needed on this topic.

Keywords: Randomized controlled trials, blood pressure, end stage rental disease

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Article Details

Year: 2012
Page: [276 - 281]
Pages: 6
DOI: 10.2174/1573402111208040276
Price: $65

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PDF: 6