Plants protect themselves from pathogen invasion through the local expression of a variety of pathogenesisrelated
proteins. They are highly diverse in both primary structure and length, and exhibit different direct antimicrobial activity.
This text reviews the knowledge of osmotin, antimicrobial protein involved in innate immunity of plants. Osmotin
belongs to the fifth class of the group of pathogenesis-related (PR) proteins and has been found in different plants species,
in every case osmotin is cysteine-rich protein involved in plant defense responses to several pathogens and abiotic
stresses. The phylogenetic tree of amino acids compositions of osmotins from different plant species is presented and the
basic similarities of clusters are discussed in this review.
Osmotin gene is activated by different biotic as well as abiotic signals and has many functions. The review summarizes
biochemical and structural properties, induction, functions and structural homology between osmotin and other proteins.
Recent data about recombinant production in bacterial and plant cells are examined.
The article indicates possible ways of osmotin application in research in the field of functional biology, medicine and agriculture.