Title:Randomized Controlled Clinical Trials in Mild-Moderate Ulcerative Colitis
VOLUME: 7 ISSUE: 4
Author(s):Maria Cappello, Claudia Randazzo and Ivana Bravata
Affiliation:Gastroenterology Section, Di.Bi.Mis, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy.
Keywords:Ulcerative colitis, treatment, controlled clinical trials
Abstract:The Authors review and critically discuss the most recent published evidence on treatment of mild-moderate
ulcerative colitis both in the induction and maintenance of remission. Evidence on each drug is introduced by the related
statement of ECCO guidelines. A brief introduction on disease classification and the need of standardizing indexes of
clinical and endoscopic activity is also provided. Concluding remarks stress the heterogeneity of available studies both in
the selection of patients and the outcomes evaluated and suggest the development of an international consensus in setting
standards which will allow studies’ results to be compared and combined to produce high quality clinical recommendations.
