Organic synthesis is a creative science involving the construction and cleavage of bond(s), which attracts
particular attention because of its immense importance to life and society. The strategies regarding construction and
cleavage of bonds represent the central theme in organic synthesis. Development of practical catalysts for efficient
synthesis is of key importance to both academia and the chemical industry. A meticulous literature survey at this stage
revealed that P2O5 has recently emerged as a powerful catalyst and has been widely utilized in various transformations.
Considering the lack of review in the area of P2O5 catalyzed organic reactions and in continuation of our efforts on more
sustainable syntheses catalyzed by P2O5 and/or P2O5 embedded on solid support, here an updated overview of the
developments in P2O5 catalyzed reactions in solvent and/or under solvent-free conditions is provided. The present report
would encompass the developments up to the end of 2011 with special emphasis on the most recent developments. In the
last section of this review, some prospects about the future developments in the field covered by this review, giving
special emphasis to those aspects that still require further research to be solved satisfactorily have been discussed.
Keywords: Catalysis, Domino reactions, Multicomponent reactions, Organic synthesis, P2O5, Solvent-free reactions, nucleic acids, arsenal, diversity-oriented synthesis, eco-friendly, pyranylation, phenolic esters, exemplifying, pseudo-iminium cation, deprotected diol
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Published on: 31 October, 2012
Page: [155 - 163]