Goal Directed Fluid Therapy

Author(s): Paul E. Marik, Himanshu Desai

Journal Name: Current Pharmaceutical Design

Volume 18 , Issue 38 , 2012

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The cornerstone of treating patients with shock remains as it has for decades, intravenous fluids. Surprisingly, dosing intravenous fluid during resuscitation of shock remains largely empirical. Recent data suggests that early aggressive resuscitation of critically ill patients may limit and/or reverse tissue hypoxia, progression to organ failure and improve outcome. However, overzealous fluid resuscitation has been associated with increased complications, increased length of intensive care unit (ICU) and hospital stay and increased mortality. This review focuses on methods to assess fluid responsiveness and the application of these methods for goal directed fluid therapy in critically ill and peri-operative patients.

Keywords: Hemodynamic monitoring, volume responsive, fluid challenge, bioreactance, passive leg raising

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Article Details

Year: 2012
Published on: 30 October, 2012
Page: [6215 - 6224]
Pages: 10
DOI: 10.2174/138161212803832399
Price: $65

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