Endoscopic Microscopy Using Optical Coherence Tomography

Author(s): Chia-Pin Liang, Chao-Wei Chen, Jeremiah Wierwille, Jaydev Desai, Rao Gullapalli, Reuben Mezrich, Cha-Min Tang, Yu Chen

Journal Name: Current Medical Imaging
Formerly: Current Medical Imaging Reviews

Volume 8 , Issue 3 , 2012

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Optical coherence tomography (OCT) can perform high-speed, micron-level high resolution imaging of tissue microstructures in vivo and in real time and can function as a type of optical biopsy to visualize the structural and functional alterations associated with various diseases. The advances in endoscopic OCT and optical coherence microscopy (OCM) provide an exciting avenue for many promising clinical applications with the potential of enhancing diagnostic capabilities and treatment efficacies. In this review paper, we first review the basic principles for time- and Fourierdomain OCT. We then survey the various endoscopic OCT technologies followed by the review of several representative clinical applications using endoscopic OCT. Lastly, we discuss endoscopic-OCT-based, multi-modality imaging approaches and their translational potentials.

Keywords: Optical Coherence Tomography (OCT), Optical Coherence Microscopy (OCM), Endoscopy

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Article Details

Year: 2012
Published on: 30 October, 2012
Page: [174 - 193]
Pages: 20
DOI: 10.2174/157340512803759910
Price: $65

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