Pentoxifylline Use in Dermatology

Author(s): Seray Kulcu Cakmak, Atil Cakmak, Muzeyyen Gonul, Arzu Kilic, Ulker Gul

Journal Name: Inflammation & Allergy - Drug Targets (Discontinued)
(Formerly Current Drug Targets - Inflammation & Allergy)

Volume 11 , Issue 6 , 2012


Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.

Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2012
Page: [422 - 432]
Pages: 11
DOI: 10.2174/187152812803590028
Price: $58

Article Metrics

PDF: 41