Title:Adenovirus Vectors and Subviral Particles for Protein and Peptide Delivery
VOLUME: 12 ISSUE: 5
Author(s):Matthias W. Kron and Florian Kreppel
Affiliation:Department of Gene Therapy, University of Ulm, Helmholtzstr. 8/1, D-89081 Ulm, Germany.
Keywords:Protein delivery, adenovirus vector, adenovirus subviral particles, peptide delivery, gene transfer vectors, vector capsids, epidermal growth factor, endosomal
Abstract:Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition,
adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into
cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications
ranging from vaccination to gene therapy.
