Pressure is a fundamental parameter which can accelerate reaction rates. The use of ultra high pressure (0.2-2 GPa) in organic
chemistry can be particularly efficient, because it can fix problems of reactivity or regio- and stereoselectivity which could appear at ambient
pressure, while being considered as an activation tool. The present review points out the last progresses in the area of glycochemistry
with this technique. Selective protection or deprotection of the hydroxyl group of saccharides are described, as well as the most studied
cycloaddition reactions, leading to the sugar-base structure dihydropyran or employing a sugar to enhance the stereoselectivity of the
reaction. The Wittig reaction, homoallylation with allylstannane and aza-Michael reaction are also presented.