Abstract
The Araucaria angustifolia (Bertolini, Otto Kuntze) tree belongs to the family Araucariaceae and is known as Brazilian pine. The female strobilus consists of seeds (the edible part of A. angustifolia) and bracts (non-developed seeds). These bracts, which represent approximately 80% of the female strobilus, have no use. It has previously been suggested that the dietary intake of antioxidants could be a useful strategy to reduce the incidence of diseases associated with oxidative stress, such as cancer, atherosclerosis and neurodegenerative disorders. This study aimed to evaluate the phenolic profile and the possible antioxidant, mutagenic and antimutagenic activities of the aqueous extract from bracts of A. angustifolia. The results showed that the extract of A. angustifolia presents important in vitro and in vivo antioxidant activity. Additionally, lower concentrations of the extract were non-mutagenic and avoided DNA damage induced by hydrogen peroxide in yeast cells. Catechin, epicatechin and rutin were the main phenolic compounds found in the extract. These results may provide new perspectives for the development of strategies with natural compounds in the nutraceutical field. In addition, the use of this waste will help maintain the environmental balance.
Keywords: Antimutagenic, antioxidant, Araucaria angustifolia, bracts, phenolic compounds, strobilus, in vitro, in vivo, Catechin, epicatechin.
Current Nutrition & Food Science
Title:Araucaria Angustifolia: A Potential Nutraceutical with Antioxidant and Antimutagenic Activities
Volume: 8 Issue: 3
Author(s): Fabiane Michelon, Catia S. Branco, Caroline Calloni, Ivana Giazzon, Fabiana Agostini, Patricia K.W. Spada and Mirian Salvador
Affiliation:
Keywords: Antimutagenic, antioxidant, Araucaria angustifolia, bracts, phenolic compounds, strobilus, in vitro, in vivo, Catechin, epicatechin.
Abstract: The Araucaria angustifolia (Bertolini, Otto Kuntze) tree belongs to the family Araucariaceae and is known as Brazilian pine. The female strobilus consists of seeds (the edible part of A. angustifolia) and bracts (non-developed seeds). These bracts, which represent approximately 80% of the female strobilus, have no use. It has previously been suggested that the dietary intake of antioxidants could be a useful strategy to reduce the incidence of diseases associated with oxidative stress, such as cancer, atherosclerosis and neurodegenerative disorders. This study aimed to evaluate the phenolic profile and the possible antioxidant, mutagenic and antimutagenic activities of the aqueous extract from bracts of A. angustifolia. The results showed that the extract of A. angustifolia presents important in vitro and in vivo antioxidant activity. Additionally, lower concentrations of the extract were non-mutagenic and avoided DNA damage induced by hydrogen peroxide in yeast cells. Catechin, epicatechin and rutin were the main phenolic compounds found in the extract. These results may provide new perspectives for the development of strategies with natural compounds in the nutraceutical field. In addition, the use of this waste will help maintain the environmental balance.
Export Options
About this article
Cite this article as:
Michelon Fabiane, S. Branco Catia, Calloni Caroline, Giazzon Ivana, Agostini Fabiana, K.W. Spada Patricia and Salvador Mirian, Araucaria Angustifolia: A Potential Nutraceutical with Antioxidant and Antimutagenic Activities, Current Nutrition & Food Science 2012; 8 (3) . https://dx.doi.org/10.2174/157340112802651103
DOI https://dx.doi.org/10.2174/157340112802651103 |
Print ISSN 1573-4013 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3881 |
Call for Papers in Thematic Issues
Functional Foods in Human Health and Beyond
Foods are important source of nutrients including carbohydrates, proteins, lipids and other minerals. Furthermore, the functional foods are those agents that have additional components that are essential supports to the body in terms of antioxidant and pharmacologically active agents. The predominant functional foods are of plant in origin, whereas some ...read more
Harnessing Bioactive Compounds from Food Waste: Sustainable Extraction Strategies and Health Applications
Food waste presents a significant challenge across the postharvest cycle, from agricultural production to distribution. However, within this waste lies a treasure trove of bioactive chemicals that hold immense potential for nutraceuticals, functional foods, and postharvest additives, including antimicrobials. Various extraction methods, such as solvent extraction (SE), supercritical fluid extraction ...read more
Natural Bioactive Compounds Derivatives in Nutraceutical and Food Science
In the last years, plants have been widely used for their numerous properties and now there is growing interest in the study of classes of compounds obtained from plant species or derived from them. The importance of these natural compounds lies in their important therapeutic purposes, and in their capability ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Novel Strategies and Tools for Enhanced Sensitivity in Routine Biomolecule Analytics
Current Pharmaceutical Analysis Nanoemulsions for Intranasal Delivery of Riluzole to Improve Brain Bioavailability: Formulation Development and Pharmacokinetic Studies
Current Drug Delivery Alteration of Isocitrate Dehydrogenase Following Acute Ischemic Injury as a Means to Improve Cellular Energetic Status in Neuroadaptation
CNS & Neurological Disorders - Drug Targets Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications
Current Organic Chemistry Animal Venom Peptides as a Treasure Trove for New Therapeutics Against Neurodegenerative Disorders
Current Medicinal Chemistry Environmental Enrichment as a Positive Behavioral Intervention Across the Lifespan
Current Neuropharmacology Can Apolipoproteins and Complement Factors be Biomarkers of Alzheimer’s Disease?
Current Alzheimer Research Amyloid β-induced Mesenteric Inflammation in an Alzheimer’s Disease Transgenic Mouse Model
Current Alzheimer Research Nitric Oxide: Target for Therapeutic Strategies in Alzheimers Disease
Current Pharmaceutical Design New Achievements in Bioinformatics Prediction of Post Translational Modification of Proteins
Current Topics in Medicinal Chemistry Regulation of GABA Neurotransmission by Glutamic Acid Decarboxylase (GAD)
Current Pharmaceutical Design Yeast as a Model System to Study Trafficking of Small Vesicles Carrying Signal-less Proteins In and Out of the Cell
Current Protein & Peptide Science Non-Steroidal Anti-Inflammatory Drugs as Anti-Amyloidogenic Compounds
Current Pharmaceutical Design Cross-Talk Between NO Synthase Isoforms in Neuro-Inflammation: Possible Implications in HIV-Associated Neurocognitive Disorders
Current Medicinal Chemistry The Role of Minocycline in Ischemia-Reperfusion Injury: A Comprehensive Review of an Old Drug with New Implications
Recent Patents on Cardiovascular Drug Discovery Applications of Exosomes in Targeted Drug Delivery for the Treatment of Parkinson’s Disease: A Review of Recent Advances and Clinical Challenges
Current Topics in Medicinal Chemistry Exploring Structural and Physicochemical Profiles of Potential GSK-3β Inhibitors Using Structure- and Ligand-Based Modeling Studies
Combinatorial Chemistry & High Throughput Screening Aluminum Induced Immunoexcitotoxicity in Neurodevelopmental and Neurodegenerative Disorders
Current Inorganic Chemistry (Discontinued) Inflammation and Age-Related Iron Accumulation in F344 Rats
Current Aging Science Commentary: Neurorestoratology: A Concept and Emerging Discipline in the Treatment of Neurological Disorders
CNS & Neurological Disorders - Drug Targets