Abstract
Cellular in vivo imaging can reveal the induction, progression and resolution of nervous system pathology in real-time. In this review, we summarize recent research in the field to illustrate how in vivo imaging has enhanced our understanding of a variety of neurological conditions caused by trauma, degeneration, ischemia or inflammation. Finally, we look ahead and discuss how novel biosensors might help us to follow not only the cellular but also the molecular pathogenesis of neurological diseases in vivo.
Keywords: In vivo imaging, multi-photon microscopy, neurodegeneration, neurotrauma, ischemia, neuroinflammation, nervous system, biosensors, cerebral cortex, reactive oxygen species.
Current Pharmaceutical Design
Title:In Vivo Imaging of the Diseased Nervous System: An Update
Volume: 18 Issue: 29
Author(s): Catherine Sorbara, Thomas Misgeld and Martin Kerschensteiner
Affiliation:
Keywords: In vivo imaging, multi-photon microscopy, neurodegeneration, neurotrauma, ischemia, neuroinflammation, nervous system, biosensors, cerebral cortex, reactive oxygen species.
Abstract: Cellular in vivo imaging can reveal the induction, progression and resolution of nervous system pathology in real-time. In this review, we summarize recent research in the field to illustrate how in vivo imaging has enhanced our understanding of a variety of neurological conditions caused by trauma, degeneration, ischemia or inflammation. Finally, we look ahead and discuss how novel biosensors might help us to follow not only the cellular but also the molecular pathogenesis of neurological diseases in vivo.
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Cite this article as:
Sorbara Catherine, Misgeld Thomas and Kerschensteiner Martin, In Vivo Imaging of the Diseased Nervous System: An Update, Current Pharmaceutical Design 2012; 18 (29) . https://dx.doi.org/10.2174/138161212802502279
DOI https://dx.doi.org/10.2174/138161212802502279 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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