A series of 1,3-oxathiolane-based nucleoside analogs 5-methyl substituted was synthesized and tested as potential
antiviral agents. Structural characterization and C2-C4 / C2-C5 relative stereochemistry assignments were
performed by NMR experiments. All tested isomers were found to be inactive and cytotoxic.
Keywords: 5-methyl-1, 3-oxathiolanes, Antiviral, NMR, Nucleosides, Stereochemistry, Synthesis, AIDS, RNA, DNA, drugs
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