1-Formyl-9H-β-Carboline: A Useful Scaffold for Synthesizing Substituted- and Fused β-Carbolines

Author(s): Virender Singh and Sanjay Batra

Journal Name: Current Organic Synthesis

Volume 9 , Issue 4 , 2012

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β-Carboline represents the core unit of several alkaloids and bioactive agents. This review assimilates the reports pertaining to the synthesis and applications of 1-formyl-9H-β-carbolines for affording 1-substituted, C-1-N-9 and C-1-N-2 fused β-carbolines.

Keywords: β-Carboline, annulated- β-carboline, canthine, canthin-6-one, Morita-Baylis-Hillman, Cycloaddition, alkaloidsm topoisomerase-II, Pictet-Spengler reaction, anticonvulsant.

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Article Details

Year: 2012
Page: [513 - 528]
Pages: 16
DOI: 10.2174/157017912802651465
Price: $65

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PDF: 12