Diabetic CVD – Focus on Vitamin D

Author(s): Shokoufeh Bonakdaran, Haleh Rokni

Journal Name: Cardiovascular & Hematological Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents)

Volume 10 , Issue 3 , 2012

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Cardiovascular disease (CVD) is the leading cause of mortality and morbidity among diabetics. Vitamin D deficiency is very common all over the world. Over last few years, vitamin D has been considered as an important regulating factor for cardiovascular health. Metabolic syndrome and obesity are highly prevalent in vitamin D deficient people. In fact all components of metabolic syndrome are affected by vitamin D. Vitamin D regulates insulin secretion and its action. It has also some controlling effect on Renin-Angiotensin system, which influences cardiomyocytes positively. Vitamin D plays a role in vascular system too. This vitamin reduces vascular calcification and inflammatory processes. Given the important role of Vitamin D in cardiovascular health, this review focuses on the impacts of vitamin D on the various CVD risk factors.

Keywords: Albuminuria, Cardiovascular Disease, congestive heart failure, Diabetes, hypertension, inflammation, insulin resistance, Metabolic Syndrome, obesity, Vitamin D

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Article Details

Year: 2012
Page: [241 - 250]
Pages: 10
DOI: 10.2174/187152512802651088
Price: $65

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