The ECG is a rapidly available clinical tool that can help clinicians manage poisoned patients. Specific myocardial
effects of cardiotoxic drugs have well-described electrocardiographic manifestations. In the practice of clinical
toxicology, classic ECG changes may hint at blockade of ion channels, alterations of adrenergic tone, or dysfunctional
metabolic activity of the myocardium. This review will offer a structured approach to ECG interpretation in poisoned patients
with a focus on clinical implications and ECG-based management recommendations in the initial evaluation of patients
with acute cardiotoxicity.
Keywords: Toxicology, electrocardiography, poisoning, electrocardiography, injury-related fatality, ECGs, QRS prolongation, TCA overdose, QT Interval, TCA toxicity, ECG
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