The Possible Mechanisms for β-glucans to Prevent Atherosclerotic Lesions

Title:The Possible Mechanisms for β-glucans to Prevent Atherosclerotic Lesions

Volume: 8 Issue: 2

Author(s): Tiphaine Gislette, Kong-Nan Zhao, Wenyi Gu and Jiezhong Chen

Affiliation:

Keywords: Atheroslerosis, β-glucans, macrophages, NO production, LDL-cholesterol, Wound healing, phagocytosis, immune resposnes, fungi, plants.

Abstract: Foods enriched in β-glucans including oat and edible fungi as well as some purified β-glucans have been shown to reduce atherosclerotic lesions. The multiple mechanisms may be involved to affect several aspects of the pathogenesis of atherosclerosis such as phagocytosis of macrophages, NO production, epithelial cell functions and blood levels of cholesterol. Structurally different β-glucans may have different effects in the pathogenesis of atherosclerosis. The study of structure-function relationship may provide an approach for optimizing β-glucans to be used in the prevention of atherosclerosis.

Cite this article as:

Gislette Tiphaine, Zhao Kong-Nan, Gu Wenyi and Chen Jiezhong, The Possible Mechanisms for β-glucans to Prevent Atherosclerotic Lesions, Current Bioactive Compounds 2012; 8 (2) . https://dx.doi.org/10.2174/157340712801784796