Recent Patents in Plant Biotechnology: Impact on Global Health

Kathleen      L. Hefferon

Abstract

Agricultural biotechnology offers a robust series of tools by which to address global concerns such as food security, crop protection, and fuel/energy requirements. A number of advances made recently in plant molecular biology also have resulted in applications which largely focus on improving global human health. This review describes some of the recent innovations in plant biotechnology that have come to the forefront over the past year. Included are novel techniques by which plants can be improved as platforms for biopharmaceutical protein production, a growing field also referred to as ‘molecular pharming’. The metabolic engineering of plants to produce compounds which have additional nutritional benefits is also outlined. The review concludes with a discussion of the future impact that these innovations may have both on global health and on the development of our future intellectual property landscape.

Keywords: Molecular pharming, vaccines, therapeutic proteins, pharmaceuticals, glycosylation, metabolic engineering, Transgenic, allergenicity, recombinant proteins, pharmaceutical proteins, GVGVP polymers, insulin, Norovirus, capsid protein