An Efficient Green MCR Protocol for the Synthesis of New Betti Bases via Mannich-Type Reaction

Author(s): Abolfazl Olyaei, Mojgan Zarnegar, Mahdieh Sadeghpour, Mortaza Rezaei

Journal Name: Letters in Organic Chemistry

Volume 9 , Issue 6 , 2012

Become EABM
Become Reviewer
Call for Editor


An efficient solvent and catalyst-free synthesis of new Betti base derivatives via Mannich-type one-pot threecomponent condensation reaction of aminodiazines, salicylaldehyde and naphthols under solvent-free conditions is described. The reactions occur at 80 oC giving high to excellent yields of the products. The work-up procedure is very simple and the products do not require further purification with column chromatography.

Keywords: Aminodiazine, Betti base, naphthol, salicylaldehyde, solvent-free, three- component, 2-aminopyrimidine, temperature, aminonaphthols

open access plus

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2012
Published on: 21 June, 2012
Page: [451 - 456]
Pages: 6
DOI: 10.2174/157017812801322499

Article Metrics

PDF: 34