Search Result "trypanothione reductase inhibitors"


A Decade of Targets and Patented Drugs for Chemotherapy of Chagas Disease

Journal: Recent Patents on Anti-Infective Drug Discovery
Volume: 6 Issue: 3 Year: 2011 Page: 216-259
Author(s): Vilma G. Duschak

Macromolecular Bases of Antischistosomal Therapy

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 2012-2028
Author(s): Francesco Angelucci, Adriana Erica Miele, Giovanna Boumis, Maurizio Brunori, Daniela Dimastrogiovanni, Andrea Bellelli

Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1284-1291
Author(s): Ian H. Gilbert, Didier Leroy, Julie A. Frearson

State of the Art in African Trypanosome Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1255-1274
Author(s): Robert T. Jacobs, Bakela Nare, Margaret A. Phillips

Editorial [Hot Topic: Mitochondria as a Pharmacological Target: A Clue for Efficacy and a Reason for Toxicity (Executive Guest Editor: Nadezda Apostolova)]

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 2 Year: 2011 Page: 1984-1985
Author(s): Nadezda Apostolova

Natural and Synthetic Naphthoquinones Active Against Trypanosoma Cruzi: An Initial Step Towards New Drugs for Chagas Disease

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 144-161
Author(s): Cristian O. Salas, Mario Faundez, Antonio Morello, Juan Diego Maya, Ricardo A. Tapia

Trypanocidal Activity of Nitroaromatic Prodrugs: Current Treatments and Future Perspectives

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 2072-2084
Author(s): Shane R. Wilkinson, Christopher Bot, John M. Kelly, Belinda S. Hall

A Prodrug Approach to Improve the Physico-Chemical Properties and Decrease the Genotoxicity of Nitro Compounds

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 3 Year: 2011 Page: 3515-3526
Author(s): Man Chin Chung, Priscila Longhin Bosquesi, Jean Leandro dos Santos

Bio-Inspired Algorithms Applied to Molecular Docking Simulations

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 9 Year: 2011 Page: 1339-1352
Author(s): G. Heberle, W. F. de Azevedo

Target Validation: Linking Target and Chemical Properties to Desired Product Profile

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1275-1283
Author(s): Paul G. Wyatt, Ian H. Gilbert, Kevin D. Read, Alan H. Fairlamb

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