Search Result "rapid liver clearance"


Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Clearance of Amyloid-β Peptide by Neuronal and Non-Neuronal Cells: Proteolytic Degradation by Secreted and Membrane associated Proteases

Journal: Current Neurovascular Research
Volume: 4 Issue: 4 Year: 2007 Page: 240-251
Author(s): Mai Panchal, Noureddine Lazar, Noeli Munoz, Christine Fahy, Christine Clamagirand, Jean-Paul Brouard, Lionel Dubost, Paul Cohen, Noureddine Brakch, Mohamed Rholam

Targeting the Liver in the Metabolic Syndrome: Evidence from Animal Models

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 2 Year: 2007 Page: 2199-2207
Author(s): Michele Petruzzelli, Giuseppe Lo Sasso, Piero Portincasa, Giuseppe Palasciano, Antonio Moschetta

Radionuclide Liver Cancer Therapies: From Concept to Current Clinical Status

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 4 Year: 2007 Page: 441-459
Author(s): Maarten A.D. Vente, Monique G.G. Hobbelink, Alfred D. van het Schip, Bernard A. Zonnenberg, Johannes F.W. Nijsen

Pharmacokinetic and Pharmacodynamic Profiles of Rapid-Acting Artemisinins in the Antimalarial Therapy

Journal: Current Drug Therapy
Volume: 2 Issue: 3 Year: 2007 Page: 210-223
Author(s): Qigui Li, Peter J. Weina, Wilbur K. Milhous

Immune Response to Helper Dependent Adenoviral Mediated Liver Gene Therapy: Challenges and Prospects

Journal: Current Gene Therapy
Volume: 7 Issue: 5 Year: 2007 Page: 297-305
Author(s): Michael P. Seiler, Vincenzo Cerullo, Brendan Lee

Statins and Metabolism of High Density Lipoprotein

Journal: Cardiovascular & Hematological Agents in Medicinal Chemistry
Volume: 5 Issue: 3 Year: 2007 Page: 215-221
Author(s): Dmitri Sviridov, Paul Nestel, Gerald Watts

Metabolic Stability Screen for Drug Discovery Using Cassette Analysis and Column Switching

Journal: Drug Metabolism Letters
Volume: 1 Issue: 1 Year: 2007 Page: 67-72
Author(s): Jason S. Halladay, Susan Wong, Sharmin M. Jaffer, Achintya K. Sinhababu, S. Cyrus Khojasteh-Bakht

Cholestasis During Pregnancy: Aetiopathogenesis, Foetal-Maternal Repercussions and Pharmacological Treatments

Journal: Current Women`s Health Reviews
Volume: 3 Issue: 4 Year: 2007 Page: 235-247
Author(s): Jose J.G. Marin, Rocio I.R. Macias, Oscar Briz, Maria J. Perez, Alba G. Blazquez, Marco Arrese, Maria A. Serrano

Transcriptional Regulation and Expression of CYP3A4 in Hepatocytes

Journal: Current Drug Metabolism
Volume: 8 Issue: 2 Year: 2007 Page: 185-194
Author(s): Celia P. Martinez-Jimenez, Ramiro Jover, M. Teresa Donato, Jose V. Castell, M. Jose Gomez-Lechon

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