Search Result "pharmacophore"


Research Article

Antidepressant Drug Design on TCAs and Phenoxyphenylpropylamines utilizing QSAR and Pharmacophore Modeling

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 23 Issue: 0 Year: 2020 Page: 1-14
Author(s): Amit Kumar,Sisir Nandi,Anil Kumar Saxena

Research Article

Ligand Based Pharmacophore Modeling Followed by Biological Screening Lead to Discovery of Novel PDK1 Inhibitors as Anticancer Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 20 Issue: 4 Year: 2020 Page: 476-485
Author(s): Iman Mansi,Mahmoud A. Al-Sha'er,Nizar Mhaidat,Mutasem Taha

Perspective Article

Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 23 Issue: 9 Year: 2020 Page: 842-846
Author(s): Bijo Mathew

Research Article

Investigation of Binding Characteristics of Phosphoinositide-dependent Kinase-1 (PDK1) Co-crystallized Ligands Through Virtual Pharmacophore Modeling Leading to Novel anti – PDK1 Hits

Journal: Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 860-880
Author(s): Iman A. Mansi,Mahmoud A. Al-Sha`er,Nizar M. Mhaidat,Mutasem O. Taha,Rand Shahin

Research Article

Exploring the selectivity profile of sigma receptor ligands by molecular docking and pharmacophore analyses

Journal: Medicinal Chemistry
Volume: 16 Issue: 0 Year: 2020 Page: 1-21
Author(s): Giada Righetti,Michele Tonelli,Paola Fossa,Elena Cichero

Research Article

Combiphore (Structure and Ligand Based Pharmacophore) - Approach for the Design of GPR40 Modulators in the Management of Diabetes

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 2 Year: 2020 Page: 233-247
Author(s): Krishna A. Gajjar,Anuradha K. Gajjar

Research Article

De-Novo Ligand Design against Mutated Huntington Gene by Ligand-based Pharmacophore Modeling Approach

Journal: Current Computer-Aided Drug Design
Volume: 16 Issue: 2 Year: 2020 Page: 134-144
Author(s): Anum Munir,Shaukat I. Malik,Khalid A. Malik

Research Article

Identification and Investigation of Chalcone Derivatives as Calcium Channel Blockers: Pharmacophore modeling, Docking studies, In-vitro screening, and 3D-QSAR Analysis

Journal: Current Computer-Aided Drug Design
Volume: 16 Issue: 0 Year: 2020 Page: 1-13
Author(s): Amol S. Sherikar,Manish S. Bhatia,Rakesh P. Dhavale

Letter Article

A Definitive Pharmacophore Modelling Study on CDK2 ATP Pocket Binders: Tracing the Path of New Virtual High-Throughput Screenings

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 5 Year: 2020 Page: 740-747
Author(s): Marco Tutone,Giulia Culletta,Luca Livecchi,Anna M. Almerico

Research Article

Molecular Docking Studies and Pharmacophore Modeling of Some Insulin Mimetic Agents from Herbal Sources: A Rational Approach towards Designing of Orally Active Insulin Mimetic Agents

Journal: Current Traditional Medicine
Volume: 6 Issue: 2 Year: 2020 Page: 121-133
Author(s): Joohee Pradhan,Sunita Panchawat

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