Search Result "p53"


Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities

Journal: Current Drug Targets
Volume: 15 Issue: 1 Year: 2014 Page: 80-89
Author(s): Bo Hong,A. Pieter J. van den Heuvel,Varun V. Prabhu,Shengliang Zhang,Wafik S. El-Deiry

Targeting MDM2-p53 Interaction for Cancer Therapy: Are We There Yet?

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 5 Year: 2014 Page: 553-574
Author(s): S. Nag,X. Zhang,K.S. Srivenugopal,M.-H. Wang,W. Wang,R. Zhang

MDM2-p53 Interaction in Paediatric Solid Tumours: Preclinical Rationale, Biomarkers and Resistance

Journal: Current Drug Targets
Volume: 15 Issue: 1 Year: 2014 Page: 114-123
Author(s): Giuseppe Barone,Deborah A. Tweddle,Jason M. Shohet,Louis Chesler,Lucas Moreno,Andrew DJ Pearson,Tom Van Maerken

The Interaction Between FAK, MYCN, p53 and Mdm2 in Neuroblastoma

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 1 Year: 2014 Page: 46-51
Author(s): Alicia M. Waters,Elizabeth A. Beierle

Germline Genetics of the p53 Pathway Affect Longevity in a Gender Specific Manner

Journal: Current Aging Science
Volume: 7 Issue: 2 Year: 2014 Page: 91-100
Author(s): Sebastian Groß,Uta-Dorothee Immel,Michael Klintschar,Frank Bartel

The Tumor Suppressor, p53 Regulates the γA-Crystallin Gene During Mouse Lens Development

Journal: Current Molecular Medicine
Volume: 14 Issue: 9 Year: 2014 Page: 1197-1204
Author(s): X.-H. Hu,Q. Nie,M. Yi,T.-T. Li,Z.-F. Wang,Z.-X. Huang,X.-D. Gong,L. Zhou,W.-K. Ji,W.-F. Hu,J.-F. Liu,L. Wang,Z. Woodward,J. Zhu,W.-B. Liu,Q.D. Nguyen,D.W.-C. Li

Stimulation of DDX3 Expression by Ginsenoside Rg3 through the Akt/p53 Pathway Activates the Innate Immune Response via TBK1/IKKε/IRF3 Signalling

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 8 Year: 2014 Page: 1050-1060
Author(s): Yeo-Jin Choi, Li-Jung Kang, Seong-Gene Lee

The Docking Based 3D-QSAR Studies on Isoindolinone Derived Inhibitors of p53-MDM2 Binding

Journal: Letters in Drug Design & Discovery
Volume: 11 Issue: 1 Year: 2014 Page: 50-58
Author(s): Huazhou Ying,Chunlei Wu,Chunqi Hu

Epigallocatechin-3-Gallate Prevents Autoimmune-Associated Down- Regulation of p21 in Salivary Gland Cells Through a p53-Independent Pathway

Journal: Inflammation & Allergy - Drug Targets (Discontinued)
Volume: 13 Issue: 1 Year: 2014 Page: 15-24
Author(s): Douglas Dickinson,Hongfang Yu,Seiji Ohno,Cristina Thomas,Scott DeRossi,Yat-Ho Ma,Nicole Yates,Emily Hahn,Frederick Bisch,Tetsuya Yamamoto,Stephen Hsu

Network Effect of Wt-mutant p53 Interactions and Implications on p53 Gene Therapy

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 8 Year: 2014 Page: 1259-1267
Author(s): Xiaona Ji, Lijie Ma, Qiang Huang, Zijuan Li, Jing Zhao, Weixue Huang, Buyong Ma, Long Yu

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