Search Result "optimization problem"


The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2001 Page: 353-366
Author(s): Gary W. Caldwell, David M. Ritchie, John A. Masucci, William Hageman, Zhengyin Yan

The Importance of Drug Delivery to Optimize the Effects of Bone Morphogenetic Proteins During Periodontal Regeneration

Journal: Current Pharmaceutical Biotechnology
Volume: 2 Issue: 2 Year: 2001 Page: 131-142
Author(s): Gaston N. King

Recent Advances on the Role of Topological Indices in Drug Discovery Research

Journal: Current Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2001 Page: 1573-1588
Author(s): Ernesto Estrada, Eugenio Uriarte

Monoclonal Antibodies in the Treatment of Hematologic Malignancies: Radiation Dosimetry Aspects

Journal: Current Pharmaceutical Biotechnology
Volume: 2 Issue: 4 Year: 2001 Page: 351-356
Author(s): M.G. Stabin, A.B. Brill

Herpes Simplex Virus Vectors for the Nervous System

Journal: Current Gene Therapy
Volume: 1 Issue: 4 Year: 2001 Page: 339-358
Author(s): C. E. Lilley, R. H. Branston, R. S. Coffin

The Molecular Genetics of Lentiviral Vectors - Current and Future Perspectives

Journal: Current Gene Therapy
Volume: 1 Issue: 3 Year: 2001 Page: 237-251
Author(s): L. J. Chang, E. E. Gay

Tailoring Bioanalysis for PK Studies Supporting Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2001 Page: 443-461
Author(s): P.M.M.B.L. Timmerman, R. de Vries, B.A. Ingelse

An Approach for the Rational Design of New Antituberculosis Agents

Journal: Current Drug Targets
Volume: 2 Issue: 4 Year: 2001 Page: 427-437
Author(s): K. F. M. Pasqualoto, E. I. Ferreira

Update on Antifolate Drugs Targets

Journal: Current Drug Targets
Volume: 2 Issue: 2 Year: 2001 Page: 135-166
Author(s): M. P. Costi, S. Ferrari

Structure-Activity Relationships of Multidrug Resistance Reversers

Journal: Current Medicinal Chemistry
Volume: 8 Issue: 6 Year: 2001 Page: 685-713
Author(s): Michael Wiese, Ilza K. Pajeva

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