Search Result "major metabolites"


LC-MS/MS-Based Approach for Obtaining Exposure Estimates of Metabolites in Early Clinical Trials Using Radioactive Metabolites as Reference Standards

Journal: Drug Metabolism Letters
Volume: 1 Issue: 4 Year: 2007 Page: 293-298
Author(s): Donglu Zhang, Nirmala Raghavan, Theodore Chando, Janice Gambardella, Yunlin Fu, Duxi Zhang, Steve E. Unger, W. Griffith Humphreys

Mass Defect Filtering on High Resolution LC/MS Data as a Methodology for Detecting Metabolites with Unpredictable Structures: Identification of Oxazole-Ring Opened Metabolites of Muraglitazar

Journal: Drug Metabolism Letters
Volume: 1 Issue: 4 Year: 2007 Page: 287-292
Author(s): Donglu Zhang, Peter T. Cheng, Haiying Zhang

Secondary Metabolites from Cordyceps Species and Their Antitumor Activity Studies

Journal: Recent Patents on Biotechnology
Volume: 1 Issue: 2 Year: 2007 Page: 123-137
Author(s): Jian-Hui Xiao, Jian-Jiang Zhong

Effect of Common NAT2 Variant Alleles in the Acetylation of the Major Clonazepam Metabolite, 7-minoclonazepam

Journal: Drug Metabolism Letters
Volume: 1 Issue: 1 Year: 2007 Page: 3-5
Author(s): M. Olivera, C. Martinez, G. Gervasini, J. A. Carrillo, S. Ramos, J. Benitez, E. Garcia-Martin, J. A. G. Agundez

The Conduct of Drug Metabolism Studies Considered Good Practice (I): Analytical Systems and In Vivo Studies

Journal: Current Drug Metabolism
Volume: 8 Issue: 8 Year: 2007 Page: 815-821
Author(s): Xiaodong Liu, Lee Jia

Endothelial Cell-Based Methods for the Detection of Cyanobacterial Anti- Inflammatory and Wound-Healing Promoting Metabolites

Journal: Drug Metabolism Letters
Volume: 1 Issue: 4 Year: 2007 Page: 254-260
Author(s): Christoph Wiesner, Jiri Kopecky, Maren Pflueger, Harald Hundsberger, Barbara Entler, Christoph Kleber, Josef Atzler, Pavel Hrouzek, Dalibor Stys, Alena Lukesova, Wolfgang Schuett, Rudolf Lucas

Chemoprotective and Carcinogenic Effects of tert-Butylhydroquinone and Its Metabolites

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 1-7
Author(s): Negar Gharavi, Susan Haggarty, Ayman O. S. El-Kadi

Role of P-Glycoprotein in the Intestinal Absorption of Tanshinone IIA, a Major Active Ingredient in the Root of Salvia miltiorrhiza Bunge

Journal: Current Drug Metabolism
Volume: 8 Issue: 4 Year: 2007 Page: 325-340
Author(s): Xi-Yong Yu, Shu-Guang Lin, Zhi-Wei Zhou, Xiao Chen, Jun Liang, Pei-Qing Liu, Wei Duan, Balram Chowbay, Jing-Yuan Wen, Chun-Guang Li, Shu-Feng Zhou

Application of In-Line Liquid Chromatography-Accurate Radioisotope Counting-Mass Spectrometry (LC-ARC-MS) to Evaluate Metabolic Profile of [3H]-Mefenamic Acid in Rat Plasma

Journal: Drug Metabolism Letters
Volume: 1 Issue: 3 Year: 2007 Page: 179-188
Author(s): Wing Lam, Cho-Ming Loi, James Atherton, Wayne Stolle, John Easter, Abdul Mutlib

Isoniazid: Metabolic Aspects and Toxicological Correlates

Journal: Current Drug Metabolism
Volume: 8 Issue: 8 Year: 2007 Page: 839-851
Author(s): Paolo Preziosi

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