Search Result "major metabolites"

In Vitro and In Vivo Metabolism of a Gamma-Secretase Inhibitor BMS-299897 and Generation of Active Metabolites in Milligram Quantities with a Microbial Bioreactor

Journal: Current Drug Metabolism
Volume: 7 Issue: 8 Year: 2006 Page: 883-896
Author(s): Donglu Zhang, Ronald Hanson, Vikram Roongta, Douglas D. Dischino, Qi Gao, Charles P. Sloan, Craig Polson, Daniel Keavy, Ming Zheng, James Mitroka, Suzanne Wehrli, Suresh Yeola

Eicosanoid Inhibitors as Therapeutic Targets for Metabolic Syndrome Related Kidney Disease

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 1 Year: 2006 Page: 73-77
Author(s): John D. Imig, Xueying Zhao

Proton Magnetic Resonance Spectroscopy as a Monitoring Tool for Electroconvulsive Therapy Effects on the Brain

Journal: Current Psychiatry Reviews
Volume: 2 Issue: 1 Year: 2006 Page: 39-49
Author(s): Alexander Sartorius, Fritz A. Henn, Gabriele Ende

Renal Cytochrome P450-Derived Eicosanoids and Hypertension

Journal: Current Hypertension Reviews
Volume: 2 Issue: 3 Year: 2006 Page: 227-236
Author(s): Mong-Heng Wang

From the Design to the Clinical Application of Thromboxane Modulators

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 8 Year: 2006 Page: 903-923
Author(s): Jean-Michel Dogne, Julien Hanson, Xavier de Leval, Domenico Pratico, Cecil R. Pace-Asciak, Pierre Drion, Bernard Pirotte, Ke-He Ruan

Characterization of an Etoposide-Glutathione Conjugate Derived from Metabolic Activation by Human Cytochrome P450

Journal: Current Drug Metabolism
Volume: 7 Issue: 8 Year: 2006 Page: 897-911
Author(s): Naiyu Zheng, Shaokun Pang, Tomoyuki Oe, Carolyn A. Felix, Suzanne Wehrli, Ian A. Blair

Eicosanoids as Therapeutic Targets in Asthma

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 9 Year: 2006 Page: 668-674
Author(s): P. Rastogi, J. McHowat

Do Insecticides have Adverse Effects on Reproduction

Journal: Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 45-56
Author(s): E. V. Younglai, Y. J . Wu, W. G. Foster

Recent Advances in the Analyses of Carotenoids and Their Role in Human Health

Journal: Current Pharmaceutical Analysis
Volume: 2 Issue: 2 Year: 2006 Page: 195-204
Author(s): E-S. M. Abdel-Aal, M. H. Akhtar

Utility of the Hybrid LTQ-FTMS for Drug Metabolism Applications

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 547-555
Author(s): Mark Sanders, Petia A. Shipkova, Haiying Zhang, Bethanne M. Warrack

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