Search Result "mTOR."


Review Article

PI3K/Akt/mTOR Intracellular Pathway and Breast Cancer: Factors, Mechanism and Regulation

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 1 Year: 2017 Page: 1633-1638
Author(s): Var Ruchi Sharma,Girish Kumar Gupta,A. K. Sharma,Navneet Batra,Daljit K. Sharma,Amit Joshi,Anil K. Sharma

Review Article

Discovery and Development of ATP-Competitive mTOR Inhibitors Using Computational Approaches

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 29 Year: 2017 Page: 4321-4331
Author(s): Yao Luo,Ling Wang

Review Article

A Comprehensive Review of mTOR-Inhibiting Pharmacotherapy for the Treatment of Non-Infectious Uveitis

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 20 Year: 2017 Page: 3005-3014
Author(s): Joshua Blair,Robert Barry,David J. Moore,Alastair K. Denniston

Research Article

3D-QSAR, Virtual Screening, Docking and Design of Dual PI3K/mTOR Inhibitors with Enhanced Antiproliferative Activity

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 20 Issue: 4 Year: 2017 Page: 292-303
Author(s): Jelena Oluić,Katarina Nikolic,Jelica Vucicevic,Zarko Gagic,Slavica Filipic,Danica Agbaba

Review Article

The PI3K/AKT/mTOR-Signal Transduction Pathway as Drug Target in Triple-Negative Breast Cancer

Journal: Clinical Cancer Drugs
Volume: 4 Issue: 1 Year: 2017 Page: 47-58
Author(s): Jens C. Hahne,Jorg B. Engel,Arnd Honig,Susanne R. Meyer,Domenico Zito,Andrea Lampis,Nicola Valeri

Research Article

Polyphyllin II Restores Sensitization of the Resistance of PC-9/ZD Cells to Gefitinib by a Negative Regulation of the PI3K/Akt/mTOR Signaling Pathway

Journal: Current Cancer Drug Targets
Volume: 17 Issue: 4 Year: 2017 Page: 376-385
Author(s): Ruzhen Zheng,Hao Jiang,Jinhui Li,Xinge Liu,Hongwei Xu

Review Article

Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer

Journal: Current Neurovascular Research
Volume: 14 Issue: 3 Year: 2017 Page: 299-304
Author(s): Kenneth Maiese

Research Article

Warming Up to New Possibilities with the Capsaicin Receptor TRPV1: mTOR, AMPK, and Erythropoietin

Journal: Current Neurovascular Research
Volume: 14 Issue: 2 Year: 2017 Page: 184-189
Author(s): Kenneth Maiese

Review Article

Targeting the Akt/PI3K Signaling Pathway as a Potential Therapeutic Strategy for the Treatment of Pancreatic Cancer

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 1 Year: 2017 Page: 1321-1331
Author(s): Safieh Ebrahimi,Mina Hosseini,Soodabeh Shahidsales,Mina Maftouh,Gordon A. Ferns,Majid Ghayour-Mobarhan,Seyed Mahdi Hassanian,Amir Avan

Research Article

Targeting Leptin as a Therapeutic Strategy against Ovarian Cancer Peritoneal Metastasis

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 8 Year: 2017 Page: 1093-1101
Author(s): Xiao Wei,Yi Liu,Cheng Gong,Teng Ji,Xiaoshui Zhou,Taoran Zhang,Dongyi Wan,Sen Xu,Ping Jin,Xin Yang,Xiaoting Li,Ding Ma,Zongyuan Yang,Qinglei Gao

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