Search Result "in-silico pharmacokinetics"


Pharmacokinetic Properties and In Silico ADME Modeling in Drug Discovery

Journal: Medicinal Chemistry
Volume: 9 Issue: 2 Year: 2013 Page: 163-176
Author(s): Kathia M. Honorio,Tiago L. Moda,Adriano D. Andricopulo

In Silico and Biochemical Analyses Identify Quinone Reductase 2 as a Target of Piceatannol

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 3 Year: 2013 Page: 4195-4202
Author(s): Tze-Chen Hsieh, Dylan John Bennett, Yong-Syu Lee, Erxi Wu, Joseph M. Wu

In Silico Prediction of Cytochrome P450-Mediated Site of Metabolism (SOM)

Journal: Protein & Peptide Letters
Volume: 20 Issue: 3 Year: 2013 Page: 279-289
Author(s): Xian Liu,Qiancheng Shen,Jing Li,Shanshan Li,Cheng Luo,Weiliang Zhu,Xiaomin Luo,Mingyue Zheng,Hualiang Jiang

Drug Metabolite Generation Using a Laboratory Evolved NADPH Independent Cytochrome P450: Application of in vitro and in silico Approaches

Journal: Drug Metabolism Letters
Volume: 7 Issue: 1 Year: 2013 Page: 68-77
Author(s): Nyaradzo T. L. Chigorimbo-Murefu,Mathew Njoroge,Stefan Louw,Grace Mugumbate,Kelly Chibale

Combining In Silico Protein Stability Calculations with Structure-Function Relationships to Explore the Effect of Polymorphic Variation on Cytochrome P450 Drug Metabolism

Journal: Current Drug Metabolism
Volume: 14 Issue: 7 Year: 2013 Page: 745-763
Author(s): Lauren Arendse,Tom L. Blundell,Jonathan Blackburn

Hypnotic Profile of Imines from Benzimidazole Chalcones: Mechanism of Synthesis, DFT Studies and in silico Screening

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 13 Issue: 3 Year: 2013 Page: 207-216
Author(s): Bijo Mathew,Jerad Suresh,Sockalingam Anbazhagan,Vinod Devaraji

Form and Function in Cyclic Peptide Natural Products: A Pharmacokinetic Perspective

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 821-836
Author(s): Andrew T. Bockus, Cayla M. McEwen, R. Scott Lokey

In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 813-820
Author(s): Morena Spreafico, Matthew P. Jacobson

A Rational Approach to Identify Inhibitors of Mycobacterium tuberculosis Enoyl Acyl Carrier Protein Reductase

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 2 Year: 2013 Page: 3878-3883
Author(s): Mahesh T Chhabria, Kailash B Parmar, Pathik S Brahmkshatriya

A Series of Propofol Analogs Design by Targeting Pentameric Ligand-gated Ion Channel In Silico Method

Journal: Protein & Peptide Letters
Volume: 20 Issue: 1 Year: 2013 Page: 1238-1245
Author(s): Jing Gao, Xiao-Hui Wu, Wei-Li Dong, Shu-Qing Wang

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