Advance Search | Bentham Science

Hepatocytes as a Tool in Drug Metabolism, Transport and Safety Evaluations in Drug Discovery

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 188-198
Author(s): M. Akram, M. A. Iquebal, K. Naimuddin, Jasminder Sahi, Susan Grepper, Cornelia Smith

Impact of Ritonavir, Atazanavir and Their Combination on the CYP3A4 Induction by Efavirenz in Primary Human Hepatocytes

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 45-50
Author(s): Ganesh M. Mugundu, Niresh Hariparsad, Pankaj B. Desai

Hepatocyte Growth Factor and Its Receptor Signalling Complex as Targets in Cancer Therapy

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 2-6
Author(s): Tracey A. Martin, Wen G. Jiang

Induction of CYP2B6 and CYP3A4 Expression by 1-Aminobenzotriazole (ABT) in Human Hepatocytes

Journal: Drug Metabolism Letters
Volume: 4 Issue: 3 Year: 2010 Page: 129-133
Author(s): Kyunghee Yang, Kwi Hye Koh, Hyunyoung Jeong

Hepatocyte Growth Factor Activation Inhibitors – Therapeutic Potential in Cancer

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 47-57
Author(s): Christian Parr, Andrew J. Sanders, Wen G. Jiang

A Multi-Endpoint Evaluation of Cytochrome P450 1A2, 2B6 and 3A4 Induction Response in Human Hepatocyte Cultures After Treatment with β - Naphthoflavone, Phenobarbital and Rifampicin

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 185-194
Author(s): J. G. Zhang, Thuy Ho, Alanna L. Callendrello, Charles L. Crespi, David M. Stresser

Morphologic Characterization of PhoenixBio® (uPA+/+/SCID) Humanized Liver Chimeric Mouse Model

Journal: Drug Metabolism Letters
Volume: 4 Issue: 3 Year: 2010 Page: 180-184
Author(s): Richard A. Peterson, David L. Krull, H. Roger Brown, Mark de Serres

The Use of HepaRG and Human Hepatocyte Data in Predicting CYP Induction Drug-Drug Interactions via Static Equation and Dynamic Mechanistic Modelling Approaches

Journal: Current Drug Metabolism
Volume: 11 Issue: 1 Year: 2010 Page: 870-885
Author(s): Ken Grime, Douglas D. Ferguson, Robert J. Riley

Assessment of Competitive and Mechanism-Based Inhibition by Clarithromycin: Use of Domperidone as a CYP3A Probe-Drug Substrate and Various Enzymatic Sources Including a New Cell-Based Assay with Freshly Isolated Human Hepatocytes

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 69-76
Author(s): Veronique Michaud, Jacques Turgeon

Development of a UGT1A1 Reporter Gene Assay for Induction Studies: Correlation Between Reporter Gene Data and Regulation of UGT1A1 in Human Hepatocytes

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 31-38
Author(s): Julius Enoru-Eta, Lilian G. Yengi, Xiaoyang He, Joseph Kubik, John Kao, Joann Scatina

Search

Find Journals, Volumes, Issues, Articles, Ebooks and Chapters

Search Result "hepatocyte"