Search Result "gefitinib"


Research Article

Molecular Modeling, Docking, Dynamics and Simulation of Gefitinib and its Derivatives with EGFR in Non-small Cell Lung Cancer

Journal: Current Computer-Aided Drug Design
Volume: 14 Issue: 3 Year: 2018 Page: 246-252
Author(s): Pulakuntla Swetha Reddy,Kiran Bharat Lokhande,Shuchi Nagar,Vaddi Damodara Reddy,P. Sushma Murthy,K. Venkateswara Swamy

Research Article

Design, Synthesis and In vitro Evaluation of Piperazine Incorporated Novel Anticancer Agents

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 8 Year: 2018 Page: 866-874
Author(s): Mahaveer Singh,Hemant R. Jadhav,Amit Kumar

Research Article

Analysis of the Relative Movements Between EGFR and Drug Inhibitors Based on Molecular Dynamics Simulation

Journal: Current Bioinformatics
Volume: 13 Issue: 3 Year: 2018 Page: 299-309
Author(s): Lijiang Chen,Bin Zou,Victor Ho Fun Lee,Hong Yan

Research Article

Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4-oxadiazole Analogues

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 121-138
Author(s): Mohamed Jawed Ahsan,Arun Choupra,Rakesh Kumar Sharma,Surender Singh Jadav,Pannala Padmaja,Mohd. Zaheen Hassan,Abdulmalik Bin Saleh Al-Tamimi,Mohammed H. Geesi,Mohammed Afroz Bakht

General Research Article

Synthesis of Novel Thieno[2,3-d]pyrimidine Derivatives and Evaluation of Their Cytotoxicity and EGFR Inhibitory Activity

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2018 Page: 747-756
Author(s): Farag A. El-Telbany,Ehab M. Gedawy,Afaf A. El-Malah,Mina E. Adly

Research Article

Synthesis and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines of thieno[2,3-d]pyrimidine Derivatives Containing Isoxazole Moiety

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 5 Year: 2018 Page: 463-474
Author(s): Jianping Yong,Canzhong Lu,Xiaoyuan Wu

Research Article

Increased Expression of IRE1α Associates with the Resistant Mechanism of Osimertinib (AZD9291)-resistant non-small Cell Lung Cancer HCC827/OSIR Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 4 Year: 2018 Page: 550-555
Author(s): Zheng-hai Tang,Min-Xia Su,Xia Guo,Xiao-Ming Jiang,Lin Jia,Xiuping Chen,Jin-Jian Lu

Review Article

Clinical Effectiveness and Cost-effectiveness of Target Therapies for Adult Patients with Locally Advanced or Metastatic Non-small Cell Lung Cancer: A Systematic Review

Journal: Current Cancer Drug Targets
Volume: 18 Issue: 5 Year: 2018 Page: 405-409
Author(s): Alessandra Bearz,Massimiliano Berretta,Umberto Tirelli

Review Article

Enteral Administration of TKIs: Report of a Response to Ceritinib in an ALK-positive NSCLC Patient and Literature Review

Journal: Current Drug Targets
Volume: 19 Issue: 1 Year: 2018 Page: 1649-1656
Author(s): Francesco Facchinetti,Paola Bordi,Paola Bini,Livia Bidin,Roberta Camisa,Marcello Tiseo

Review Article

Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective

Journal: Current Drug Metabolism
Volume: 19 Issue: 1 Year: 2018 Page: 1021-1041
Author(s): Joana Goncalves,Joana Bicker,Gilberto Alves,Ana Fortuna,Amilcar Falcao

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