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Oxidative Biotransformation of Fatty Acids by Cytochromes P450: Predicted Key Structural Elements Orchestrating Substrate Specificity, Regioselectivity and Catalytic Efficiency

Journal: Current Drug Metabolism
Volume: 11 Issue: 1 Year: 2010 Page: 85-104
Author(s): Peter Hlavica, Michael Lehnerer

Application of Cytochrome P450 Drug Interaction Screening in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 145-158
Author(s): Robert S. Foti, Larry C. Wienkers, Jan L. Wahlstrom

Update Information on Drug Metabolism Systems— 2009, Part II. Summary of Information on the Effects of Diseases and Environmental Factors on Human Cytochrome P450 (CYP) Enzymes and Transporters

Journal: Current Drug Metabolism
Volume: 11 Issue: 1 Year: 2010 Page: 4-84
Author(s): Slobodan Rendic, F. Peter Guengerich

Characterization of CYP3A Isozymes Involved in the Metabolism of Domperidone: Role of Cytochrome b5 and Inhibition by Ketoconazole

Journal: Drug Metabolism Letters
Volume: 4 Issue: 2 Year: 2010 Page: 95-103
Author(s): Veronique Michaud, Chantale Simard, Jacques Turgeon

Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 199-222
Author(s): Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen, Cindy Q. Xia

Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution

Journal: Current Drug Metabolism
Volume: 11 Issue: 8 Year: 2010 Page: 678-685
Author(s): Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, Hiroshi Yamazaki

Addendum

Journal: Current Drug Metabolism
Volume: 11 Issue: 6 Year: 2010 Page: 560-560
Author(s): Bentham Science Publishers

Pharmacogenetics of Phase I and Phase II Drug Metabolism

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 204-219
Author(s): Severine Crettol, Nenad Petrovic, Michael Murray

How and Why to Screen for CYP2D6 Interindividual Variability in Patients Under Pharmacological Treatments

Journal: Current Drug Metabolism
Volume: 11 Issue: 3 Year: 2010 Page: 276-282
Author(s): Manuela De Gregori, Massimo Allegri, Simona De Gregori, Giulia Garbin, Carmine Tinelli, Mario Regazzi, Stefano Govoni, Guglielmina Nadia Ranzani

Drug and Medical Device Interactions: Stent Thrombosis and Personalizing Clopidogrel Therapy

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 8 Issue: 2 Year: 2010 Page: 124-138
Author(s): Betti Giusti, Anna Maria Gori, Rossella Marcucci, Claudia Saracini, Anna Vestrini, Rosanna Abbate

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