Search Result "Computer-aided drug design"


History and Evolution of the Pharmacophore Concept in Computer-Aided Drug Design

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 1 Year: 2002 Page: 1321-1332
Author(s): Osman F. Guner

Structure-Based Inhibitor Design Targeting HIV-1 Integrase

Journal: Current Drug Targets - Infectious Disorders
Volume: 2 Issue: 3 Year: 2002 Page: 217-234
Author(s): I-Jen Chen, Nouri Neamati, Alexander D. MacKerell, Jr.

Molecular Modeling in Cysteine Protease Inhibitor Design

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 1 Year: 2002 Page: 1673-1681
Author(s): Mika K. Lindvall

Protein Flexibility is an Important Component of Structure-Based Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 1 Year: 2002 Page: 1571-1578
Author(s): Heather A. Carlson

Rational Design of Reversible Acetylcholinesterase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 2 Issue: 1 Year: 2002 Page: 27-36
Author(s): Xavier Barril, Susana G. Kalko, Modesto Orozco, F. Javier Luque

Rational Design and Development of RDP58

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 2 Year: 2002 Page: 2217-2229
Author(s): Suhasini Iyer, Roger Lahana, Roland Buelow

Application of High-Throughput, Molecular-Targeted Screening to Anticancer Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 3 Year: 2002 Page: 229-246
Author(s): Robert H. Shoemaker, Dominic A. Scudiero, Giovanni Melillo, Michael J. Currens, Anne P. Monks, Alfred A. Rabow, David G. Covell, Edward A. Sausville

Combinations Against Combinations: Associations of Anti-HIV 1 Reverse Transcriptase Drugs Challenged by Constellations of Drug Resistance Mutations

Journal: Current Drug Metabolism
Volume: 3 Issue: 1 Year: 2002 Page: 73-95
Author(s): Giovanni Maga, Silvio Spadari

Sulfonamides and Sulfonylated Derivatives as Anticancer Agents

Journal: Current Cancer Drug Targets
Volume: 2 Issue: 1 Year: 2002 Page: 55-75
Author(s): Angela casini, Andrea Scozzafava, Antonio Mastrolorenzo, Claudiu T. Supuran

The Use of Computational Methods in the Discovery and Design of Kinase Inhibitors

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 1 Year: 2002 Page: 1527-1545
Author(s): John R. Woolfrey, G. Scott Weston

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