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Strategies to In Vitro Assessment of Major Human CYP Enzyme Activities by Using Liquid Chromatography Tandem Mass Spectrometry

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 12-19
Author(s): A. Lahoz, M. T. Donato, J. V Castell, M. J. Gomez-Lechon

Cytochrome P450-Activated Prodrugs: Targeted Drug Delivery

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2346-2365
Author(s): Kristiina M. Huttunen, Niina Mahonen, Hannu Raunio, Jarkko Rautio

Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions

Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 384-393
Author(s): Jiansong Yang, Mingxiang Liao, Magang Shou, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker, Amin Rostami-Hodjegan

Personalized Medicine: Pharmacogenetics in Psychiatry

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 6 Issue: 1 Year: 2008 Page: 1-11
Author(s): Jan van der Weide, John W.J. Hinrichs

Modulation of Cardiac and Hepatic Cytochrome P450 Enzymes During Heart Failure

Journal: Current Drug Metabolism
Volume: 9 Issue: 2 Year: 2008 Page: 122-128
Author(s): Ayman O.S. El-Kadi, Beshay N.M. Zordoky

Assessment of Cytochrome P450 Induction in Human Hepatocytes Using the Cocktail Strategy Plus Liquid Chromatography Tandem Mass Spectrometry

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 205-209
Author(s): Agustin Lahoz, Maria Teresa Donato, Laura Picazo, Jose V. Castell, Maria Jose Gomez-Lechon

Metabolism of Atypical Antipsychotics: Involvement of Cytochrome P450 Enzymes and Relevance for Drug-Drug Interactions

Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 410-418
Author(s): Liana Urichuk, Trevor I. Prior, Serdar Dursun, Glen Baker

Purification, Crystallization and Preliminary Crystallographic Analysis of CYP 195A2, a P450 Enzyme from Rhodopseudomonas palustris

Journal: Protein & Peptide Letters
Volume: 15 Issue: 4 Year: 2008 Page: 423-426
Author(s): Delin Guo, Feng Xu, Stephen G. Bell, Xiaoyun Pang, Mark Bartlam, Luet-Lok Wong

Oxidative Bioactivation and Toxicity of Leflunomide in Immortalized Human Hepatocytes and Kinetics of the Non-Enzymatic to Its Major etabolitie, A77 1726

Journal: Drug Metabolism Letters
Volume: 2 Issue: 3 Year: 2008 Page: 153-157
Author(s): Quee Ming Seah, Lee-Sun New, Eric C.Y. Chan, Urs A. Boeslsterli

Applications and Limitations of Genetically Modified Mouse Models in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 419-438
Author(s): Jiunn H. Lin

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