Search Result "rapid liver clearance"


Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat

Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 91-100
Author(s): Peter W. Fan, Jacob Z. Chen, M. Allan Jaochico, Hank La, Ning Liu, Teresa Mulder, Robert T. Cass, Matthew Durk, Kirsten Messick, Nicole Valle, Shannon Liu, Wendy Lee, James J. Crawford, Joachim Rudolf, Lesley J. Murray, S. Cyrus Khojasteh, Matthew Wright

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 0 Year: 2021 Page: 1-11
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Host Background Factors Contributing to Hepatitis C Virus Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 4 Issue: 3 Year: 2003 Page: 185-193
Author(s): Maria G. Isaguliants, Natalia N. Ozeretskovskaya

99mTc-N-DBODC5: A Novel Myocardial Perfusion Imaging Agent for Diagnosis of Coronary Artery Disease, a Review

Journal: Recent Patents on Cardiovascular Drug Discovery (Discontinued)
Volume: 1 Issue: 2 Year: 2006 Page: 161-166
Author(s): Tohoru Takeda, Jin Wu, Thet-Thet-Lwin

A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 5 Year: 2015 Page: 442-452
Author(s): Lance Heinle,Vincent Peterkin,Sonia M. de Morais,Gary J. Jenkins,Ilaria Badagnani

Liver Regeneration

Ebook: Frontiers in Stem Cell and Regenerative Medicine Research

Volume: 7 Year: 2017
Author(s): Ali-Reza Sadri,Saeid Amini-Nik,Marc G Jeschke
Doi: 10.2174/9781681085524117070006

Hepatitis C Virus Clearance: The Enigma of Failure Despite an Impeccable Survival Strategy

Journal: Current Pharmaceutical Biotechnology
Volume: 4 Issue: 3 Year: 2003 Page: 169-183
Author(s): Maria G. Isaguliants

Recurrent Hepatitis C After Liver Transplantation

Journal: Anti-Infective Agents
Volume: 10 Issue: 1 Year: 2012 Page: 34-40
Author(s): Sandeep Mukherjee

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