Search Result "mek1"


Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations

Journal: Letters in Drug Design & Discovery
Volume: 11 Issue: 7 Year: 2014 Page: 894-907
Author(s): Huanhuan Shi, Lu Zhou, Guangkai Bao, Qianying Yi, Suwen Zhou, Yahui Tian, Xiaoli Li

Letter Article

Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry

Journal: Protein & Peptide Letters
Volume: 28 Issue: 5 Year: 2021 Page: 481-488
Author(s): Min Woo Yun,Kiae Kim,Ji Young Park,Ka Young Chung

Synthesis and Biological Evaluations of 3-Benzothiazol-2-yl Coumarin Derivatives as MEK1 Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 8 Year: 2013 Page: 727-732
Author(s): Chao Wang,Fengrong Xu,Yan Niu,Yun Wu,Jing Sun,Yihong Peng,Lei Liang,Ping Xu

Contribution of MEK1/ERK1/2/iNOS Pathway to Oxidative Stress and Decreased Caspase-3 Activity in Endotoxemic Rats

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 11 Issue: 3 Year: 2012 Page: 243-252
Author(s): Belma Korkmaz,Tuba Cuez,C. Kemal Buharalioglu,Abdullah T. Demiryurek,Seyhan Sahan-Firat,A. Nihal Sari,Bahar Tunctan

Review Article

The Therapeutic Potential of MEK1/2 Inhibitors in the Treatment of Gynecological Cancers: Rational Strategies and Recent Progress

Journal: Current Cancer Drug Targets
Volume: 20 Issue: 6 Year: 2020 Page: 417-428
Author(s): Sadaf Ghanaatgar-Kasbi,Majid Khazaei,Azam Rastgar-Moghadam,Gordon A. Ferns,Seyed Mahdi Hassanian,Amir Avan

HIV-1 Nef Mediates Pak Phosphorylation of Mek1 Serine298 and Elicits an Active Phospho-state of Pak2

Journal: Current HIV Research
Volume: 11 Issue: 3 Year: 2013 Page: 198-209
Author(s): Arlette Kouwenhoven,Violette Der Minassian,Jon W. Marsh

CBP-dependent Wnt/β-catenin signaling is crucial in regulation of MDR1 transcription

Journal: Current Cancer Drug Targets
Volume: 15 Issue: 6 Year: 2015 Page: 519-532
Author(s): Zanxian Xia,Mingquan Guo,Han Liu,Luwei Jiang,Qiaoxia Li,Jian Peng,Jia-Da Li,Baoen Shan,Pinghui Feng,Hong Ma

Research Article

Dauricine Inhibits Non-small Cell Lung Cancer Development byRegulating PTEN/AKT/mTOR and Ras/MEK1/2/ERK1/2 Pathways in aFLT4-dependent Manner

Journal: Current Cancer Drug Targets
Volume: 24 Issue: 0 Year: 2024 Page: 1-12
Author(s):

Review Article

The Therapeutic Potential of MAPK/ERK Inhibitors in the Treatment of Colorectal Cancer

Journal: Current Cancer Drug Targets
Volume: 21 Issue: 1 Year: 2021 Page: 932-943
Author(s): Mehran Pashirzad,Reihaneh Khorasanian,Maryam Mahmoudi Fard,Mohammad-Hassan Arjmand,Hadis Langari,Majid Khazaei,Saman Soleimanpour,Majid Rezayi,Gordon A. Ferns,Seyed Mahdi Hassanian,Amir Avan

RAS/RAF/MEK Inhibitors in Oncology

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 8 Year: 2012 Page: 1164-1176
Author(s): , M. Broggini

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