Search Result "duocarmycins"


Duocarmycins - Natures Prodrugs?

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 1 Year: 2002 Page: 1375-1389
Author(s): Mark Searcey

A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 15 Issue: 5 Year: 2015 Page: 616-630
Author(s): Pravin C. Patil,Vijay Satam,Moses Lee

Novel Analogues of CC-1065 and the Duocarmycins for the Use in Targeted Tumour Therapies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 3 Year: 2009 Page: 304-325
Author(s): Lutz F. Tietze, Birgit Krewer

A Novel Achiral seco-Amino-Cyclopropylindoline (CI) Analog of CC-1065 and the Duocarmycins: Design, Synthesis and Biological Studies

Journal: Medicinal Chemistry
Volume: 1 Issue: 1 Year: 2005 Page: 13-19
Author(s): James L. Toth, John D. Trzupek, Lloyd V. Flores, Konstantinos Kiakos, John A. Hartley, William T. Pennington, Moses Lee

Chemical and Biological Explorations of the Family of CC-1065 and the Duocarmycin Natural Products

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1494-1524
Author(s): Nandita Ghosh, Helen M. Sheldrake, Mark Searcey, Klaus Pors

Novel (S)-(-)- and R-(+)-seco-iso-cyclopropylfurano[e]indoline-5,6,7- trimethoxyindole-2-carboxamide (iso-CFI) Analogs of Duocarmycin C2: Synthesis and Biological Evaluation

Journal: Medicinal Chemistry
Volume: 2 Issue: 2 Year: 2006 Page: 139-146
Author(s): John A. Hartley, Moses Lee, Konstantinos Kiakos, Stephen Hudson, Heather Townes, Kaitlin Summerville, Adrienne Scott, Brian Lingerfelt, Bethany Purnell

Research Article

Antibody-drug Conjugate PCMC1D3-Duocarmycin SA as a Novel TherapeuticEntity for Targeted Treatment of Cancers Aberrantly ExpressingMET Receptor Tyrosine Kinase

Journal: Current Cancer Drug Targets
Volume: 22 Issue: 4 Year: 2022 Page: 312-327
Author(s): Rachel Hudson,Sreedhar Reddy Suthe,Dhavalkumar Patel,Ming-Hai Wang

Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMT

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 3 Year: 2011 Page: 3527-3547
Author(s): Lutz F. Tietze, Kianga Schmuck

Amplification of Anticancer Drug-Induced DNA Damage and Apoptosis by DNA-Binding Compounds

Journal: Current Medicinal Chemistry - Anti-Cancer Agents
Volume: 4 Issue: 5 Year: 2004 Page: 415-419
Author(s): Shosuke Kawanishi, Yusuke Hiraku

Nitroreductase-based GDEPT

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 1 Year: 2002 Page: 1349-1361
Author(s): William A. Denny

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